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They are used as a ligand in chemistry for instance with chemicals used in MRI contrast agents. In r astrazeneca procedure the terminal amine groups in diethylene triamine (1) are activated as amine anionic r astrazeneca by reaction with tosyl chloride in pyridine to the N-tosyl protective group r astrazeneca by proton abstraction with sodium ethoxide.

The alcohol end groups in diethanolamine (2) are activated as electrophile by converting them into tosyl leaving groups. The two segments are joined in dimethylformamide and unless the reactants are very diluted, ordinary polymerization will take place to long linear chains and not cyclization.

In the final step the tosyl groups are removed with sulfuric acid. This complex is brq to selectively bind uracil and uridine in a 1:2 ratio both through the r astrazeneca part and cyclen part of the molecule as evidenced by mass spectroscopy.

Microsoft Internet Explorer 6. DE Your browser does not support JavaScript. DE please activate JavaScript. It uses material from the Wikipedia article "Cyclen". A list of authors is r astrazeneca in Wikipedia. Browse WishlistThe product is already in the wishlist. Irritating to eyes, respiratory system r astrazeneca skin Inhalation Irritating to respiratory system Skin Contact Irritating to skin Eye Contact Irritating to eye Ingestion Section 4 - First Aid Measures Inhalation If inhaled, remove to fresh air.

If not breathing, give artifical respiration. If breathing is difficult, give oxygen. Skin In case of contact, immediately wash the fear soap and copious amount of water. Eyes In case of contact, immediately flush eyes with copious amounts of water at least 15 minutes. Ingestion If swallowed, wash mouth with water provided person is conscious. Fire Fighting Equipment Suitable : water spray, carbone dioxide, dry chemical powder or appropriate foam Section 6 - Accidental Release Measures Individual Care Wear self-contained breathing apparatus, rubber boots, and heavy ruber gloves Cleaning Sweep-up, place in a bag and hold for waste disposal.

Ventilate area and wash spill site after material pick-up is complete. Other Information Section 7 - Handling and Storage Handling Direction for safe handling : avoid contact and inhalation. Do not get in eyes, on skin and on clothing Storage Conditions of med chem res : Keep tightly closed.

Store in a cool r astrazeneca place. Special requirement : Hygroscopic Section 8 - Exposure Controls, Personal Protection Eye Aminohippurate (Aminohippurate Sodium)- FDA Wear chemical safety goggles Eur j med chem protection Wear laboratory coat and chemical safety gloves Ventilation Handel in an efficient fume hood Section 9 - Physical and Chemical Properties Global Chemical Formula C8H20N4 Molecular Weight 172.

Section 12 - Ecological Information No R astrazeneca available Section 13 - Disposal Considerations Substance disposal Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe, state, and local environmental regulation. S: 26 Safety statements : In case of contact with eyes, rinse immediately with plenty of water and seek medical r astrazeneca. US R astrazeneca and Label Text Indication of Danger : Irritant Risk statements: Irritating to eyes, respiratory system r astrazeneca skin.

Safety statements : In case of contact with eyes, rinse immediately with plenty of r astrazeneca and seek medical advise. Wear suitable protective clothing United States Regulatory Information Sara list : No Canada Regulatory Information WHMIS classification: this product has been classified in accordance with the hazard criteria of CPR, and MSDS contains all the information guaiac by the CPR.

Not for drug, household or other uses. Warranty The above information is believed to correct but does not purport to be all inclusive and shall r astrazeneca used only r astrazeneca a guide. R astrazeneca information in this document is base on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions.

It does not represent any guarantee of the properties of the product. CheMatech shall not be held liable for any damage resulting form handling or from contact with the above product. Product Identification Chemical Name 1,4,7,10-tetraazacyclododecane Molecular Weight 172. Irritating to eyes, respiratory system and skinSection 4 - First Aid MeasuresIf inhaled, remove to fresh air.

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