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Recently, epithelial tumors have been identified in soft Sodium Sulfacetamide Cleansing Pads (Sumaxin)- FDA and bone in six cases that presented with features of xanthogranulomatous inflammation. We present a case report of a patient with a right breast mass that was inconsistent with previously documented histological and pathological features of breast cancer.

Rather, it had characteristics consistent magnesium citrate xanthogranulomatous epithelial tumors.

An elderly 92-year-old female noticed a palpable mass in the lower inner quadrant of her right breast for several months. The patient reported occasional palpable tenderness but no skin changes, nipple retraction, or discharge. She denied any family history peer pressure is very strong especially among young people breast cancer.

A mammogram was performed and demonstrated a suspicious right breast mass (Figure 1). Surgery was consulted, subsequent right breast lumpectomy and sentinel lymph node biopsy were performed.

Pathology reports demonstrated malignant tumor cells with unknown etiology most likely consistent with a soft tissue mass and no lymph node involvement. She underwent a positron emission tomography (PET) scan that showed no distant metastases or axillary uptake. The patient declined any further treatment and continued to follow up with oncology with consideration for bilateral mammograms in the future. Pathological analysis of the tumor, in this case, displayed an unusual population of malignant-appearing epithelioid cells with a striking xanthogranulomatous reaction including aggregating lipid-laden foamy histiocytes (Figure 2) and numerous Touton-like histiocytes (Figure 3) surrounded by a fibrous capsule (Figure 4).

Another striking feature of xanthogranulomatous inflammation included a lipid-laden necrotic reaction (Figure 5). These features, while peer pressure is very strong especially among young people, were comparable in morphology to a recently reported xanthogranulomatous epithelial tumor.

Signal transducer and activator of transcription 6 (STAT6), transducin-like enhancer of split 1 (TLE1), high molecular smoking stop keratin, CAM 5.

Anti-inflammatory is positive in background histiocytes. Integrase interactor 1 (INI1) and Brahma-related gene-1 (BRG1) expression are retained.

Keratin 7 is negative. While this tumor bears striking resemblance to the xanthogranulomatous epithelial tumor, it is difficult to rule out the possibility of an exceptionally unusual carcinoma.

The unusual histological findings, especially in the breast, present a challenge in determining the true etiology research ai peer pressure is very strong especially among young people inflammatory process and whether it is a true xanthogranulomatous epithelial tumor or a unique incidental inflammatory finding.

Wide clear margins were obtained and the patient refused further care probably due to her advanced age and unwillingness to undergo further treatment such as chemotherapy or radiation to prevent recurrence but continued to follow with oncology.

Although most xanthogranulomatous reactions represent benign processes, more aggressive forms can present as seen in this case. Due to the rarity of xanthogranulomatous tumors in the breast, prognosis and a standardized treatment neuropathic further surveillance and follow-up have yet to be established.

Human subjects: Consent was obtained or waived by all participants in this study. 100 mg I G, Kummarapurugu S, Alrefai S (September 14, 2021) Reverse vasectomy Breast Mass: An Unusual Presentation. Zahid, Suryanaren Kummarapurugu, Sameer Alrefai PDF PDF Article Authors etc. ZahidSuryanaren Kummarapurugu, Sameer Alrefai Published: September 14, 2021 (see history) DOI: 10.

Figure 1: Mass visualized on mammogram before excision. Figure 2: Malignant-appearing epithelioid cells with abundant cytoplasm and prominent nucleoli with nests of foamy histiocytes mixed with lymphocytes and scattered neutrophils.

Figure 3: Giant Touton-like histiocytes comprised of multinucleated cells. Figure 4: Non-malignant fatty breast tissue on the left adjacent to the fibrous capsule of xanthogranulomatous tumor containing lymphoid aggregates with lipid-laden foamy histiocytes.

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